LymphedemaV1, Main, Exploration, bibRecord, 003542

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Identifieur interne : 003542 ( Main/Exploration ); précédent : 003541; suivant : 003543

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Auteurs : Jean-Leon Thomas ; Kasey Baker ; Jinah Han ; Charles Calvo ; Harri Nurmi ; Anne C. Eichmann ; Kari Alitalo [Finlande]

Source :

Cellular and molecular life sciences : CMLS [ 1420-682X ] ; 2013.

RBID : PMC:3648205

Abstract

Notch cell interaction mechanism governs cell fate decisions in many different cell contexts throughout the lifetime of all Metazoan species. It links the fate of one cell to that of its neighbors through cell-to-cell contacts, and binding of Notch receptors expressed on one cell to their membrane bound ligands on an adjacent cell. Environmental cues, such as growth factors and extracellular matrix molecules, superimpose a dynamic regulation on this canonical Notch signaling pathway. In this review, we will focus on Notch signaling in the vertebrate vascular and nervous systems and examine its role in angiogenesis, neurogenesis, and neurovascular interactions. We will also highlight the molecular relationships of the Notch pathway with vascular endothelial growth factors (VEGFs) and their high-affinity tyrosine kinase VEGF receptors, key regulators of both angiogenesis and neurogenesis.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648205

DOI: 10.1007/s00018-013-1312-6
PubMed: 23479133
PubMed Central: 3648205

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells</title>
<author><name sortKey="Thomas, Jean Leon" sort="Thomas, Jean Leon" uniqKey="Thomas J" first="Jean-Leon" last="Thomas">Jean-Leon Thomas</name>
</author>
<author><name sortKey="Baker, Kasey" sort="Baker, Kasey" uniqKey="Baker K" first="Kasey" last="Baker">Kasey Baker</name>
</author>
<author><name sortKey="Han, Jinah" sort="Han, Jinah" uniqKey="Han J" first="Jinah" last="Han">Jinah Han</name>
</author>
<author><name sortKey="Calvo, Charles" sort="Calvo, Charles" uniqKey="Calvo C" first="Charles" last="Calvo">Charles Calvo</name>
</author>
<author><name sortKey="Nurmi, Harri" sort="Nurmi, Harri" uniqKey="Nurmi H" first="Harri" last="Nurmi">Harri Nurmi</name>
</author>
<author><name sortKey="Eichmann, Anne C" sort="Eichmann, Anne C" uniqKey="Eichmann A" first="Anne C." last="Eichmann">Anne C. Eichmann</name>
</author>
<author><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name>
<affiliation><country>Finlande</country>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
<orgName type="university">Université d'Helsinki</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23479133</idno>
<idno type="pmc">3648205</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648205</idno>
<idno type="RBID">PMC:3648205</idno>
<idno type="doi">10.1007/s00018-013-1312-6</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">003A56</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003A56</idno>
<idno type="wicri:Area/Pmc/Curation">003A55</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003A55</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002257</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002257</idno>
<idno type="wicri:Area/Ncbi/Merge">005685</idno>
<idno type="wicri:Area/Ncbi/Curation">005685</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005685</idno>
<idno type="wicri:doubleKey">1420-682X:2013:Thomas J:interactions:between:vegfr</idno>
<idno type="wicri:Area/Main/Merge">003548</idno>
<idno type="wicri:Area/Main/Curation">003542</idno>
<idno type="wicri:Area/Main/Exploration">003542</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells</title>
<author><name sortKey="Thomas, Jean Leon" sort="Thomas, Jean Leon" uniqKey="Thomas J" first="Jean-Leon" last="Thomas">Jean-Leon Thomas</name>
</author>
<author><name sortKey="Baker, Kasey" sort="Baker, Kasey" uniqKey="Baker K" first="Kasey" last="Baker">Kasey Baker</name>
</author>
<author><name sortKey="Han, Jinah" sort="Han, Jinah" uniqKey="Han J" first="Jinah" last="Han">Jinah Han</name>
</author>
<author><name sortKey="Calvo, Charles" sort="Calvo, Charles" uniqKey="Calvo C" first="Charles" last="Calvo">Charles Calvo</name>
</author>
<author><name sortKey="Nurmi, Harri" sort="Nurmi, Harri" uniqKey="Nurmi H" first="Harri" last="Nurmi">Harri Nurmi</name>
</author>
<author><name sortKey="Eichmann, Anne C" sort="Eichmann, Anne C" uniqKey="Eichmann A" first="Anne C." last="Eichmann">Anne C. Eichmann</name>
</author>
<author><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name>
<affiliation><country>Finlande</country>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
<orgName type="university">Université d'Helsinki</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Cellular and molecular life sciences : CMLS</title>
<idno type="ISSN">1420-682X</idno>
<idno type="eISSN">1420-9071</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Notch cell interaction mechanism governs cell fate decisions in many different cell contexts throughout the lifetime of all Metazoan species. It links the fate of one cell to that of its neighbors through cell-to-cell contacts, and binding of Notch receptors expressed on one cell to their membrane bound ligands on an adjacent cell. Environmental cues, such as growth factors and extracellular matrix molecules, superimpose a dynamic regulation on this canonical Notch signaling pathway. In this review, we will focus on Notch signaling in the vertebrate vascular and nervous systems and examine its role in angiogenesis, neurogenesis, and neurovascular interactions. We will also highlight the molecular relationships of the Notch pathway with vascular endothelial growth factors (VEGFs) and their high-affinity tyrosine kinase VEGF receptors, key regulators of both angiogenesis and neurogenesis.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Finlande</li>
</country>
<region><li>Uusimaa</li>
</region>
<settlement><li>Helsinki</li>
</settlement>
<orgName><li>Université d'Helsinki</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Baker, Kasey" sort="Baker, Kasey" uniqKey="Baker K" first="Kasey" last="Baker">Kasey Baker</name>
<name sortKey="Calvo, Charles" sort="Calvo, Charles" uniqKey="Calvo C" first="Charles" last="Calvo">Charles Calvo</name>
<name sortKey="Eichmann, Anne C" sort="Eichmann, Anne C" uniqKey="Eichmann A" first="Anne C." last="Eichmann">Anne C. Eichmann</name>
<name sortKey="Han, Jinah" sort="Han, Jinah" uniqKey="Han J" first="Jinah" last="Han">Jinah Han</name>
<name sortKey="Nurmi, Harri" sort="Nurmi, Harri" uniqKey="Nurmi H" first="Harri" last="Nurmi">Harri Nurmi</name>
<name sortKey="Thomas, Jean Leon" sort="Thomas, Jean Leon" uniqKey="Thomas J" first="Jean-Leon" last="Thomas">Jean-Leon Thomas</name>
</noCountry>
<country name="Finlande"><region name="Uusimaa"><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003542 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003542 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3648205
   |texte=   Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:23479133" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.